Age-Related & Acquired Retinal Conditions

Retinal Artery Occlusion (RAO)

Retinal Artery Occlusion (RAO) occurs when an artery supplying blood to the retina becomes blocked. Because the retina depends on a continuous supply of oxygen-rich blood, a blockage can cause sudden vision loss and requires urgent medical assessment.

Understanding Retinal Artery Occlusion

Retinal Artery Occlusion (RAO) is an acquired retinal vascular condition that occurs when an artery supplying blood to the retina becomes blocked. This interrupts the flow of oxygen-rich blood to retinal tissue and can cause sudden, potentially significant vision loss. The impact depends on the location and extent of the blockage.

There are two main types of RAO:

  • Central Retinal Artery Occlusion (CRAO): A blockage of the main artery supplying the retina, which can affect a large area of retinal tissue and cause severe vision loss.
  • Branch Retinal Artery Occlusion (BRAO): A blockage of a smaller retinal artery branch, affecting the area of the retina supplied by that vessel. The impact on vision depends on whether the macula, responsible for detailed central vision, is affected.

RAO is a medical emergency. Sudden vision loss requires immediate medical assessment, as prompt evaluation is also important to identify and manage any underlying vascular or cardiovascular causes.

Retina International works with people affected by retinal conditions, patient organisations, researchers, clinicians and healthcare partners worldwide to improve awareness, support access to care and ensure patient experiences inform research and innovation.

2 main types

RAO is generally classified as central or branch retinal artery occlusion.

Sudden onset

Vision loss can occur suddenly, often affecting one eye.

An eye emergency

Sudden vision loss from suspected RAO requires urgent medical assessment.

Symptoms

How Can RAO Affect Vision

RAO can cause sudden vision loss in one eye, with the extent of impairment depending on which part of the retina is affected.
Sudden vision loss

Vision may become significantly reduced over a short period of time, usually affecting one eye.

Missing areas of vision

A person may notice a dark or blank area where part of their vision is reduced or absent.

Reduced visual clarity

Vision may become less sharp, making it harder to see objects and details clearly.

Reduced contrast

Differences between light and dark areas may become harder to distinguish.

Changes in colour vision

Colours may appear less vivid or more difficult to distinguish.

Impact on daily activities

Vision loss may affect reading, mobility, recognising faces, driving and other everyday tasks.

Diagnosis

Identifying Retinal Artery Occlusion

Diagnosis involves an urgent retinal examination and may include OCT, OCT angiography and fluorescein angiography to assess retinal blood flow and damage.
Retinal examination

An eye specialist examines the retina for signs of reduced blood supply and retinal damage.

OCT imaging

OCT provides detailed images of the retina and can help identify changes caused by reduced blood flow.

OCT Angiography

OCTA can provide information about blood flow and the retinal vascular network.

Fluorescein angiography

This imaging test can help identify areas where retinal blood flow is reduced or blocked.

Cardiovascular assessment

Blood pressure, diabetes, cholesterol and other vascular risk factors may be assessed to help identify possible causes and reduce future risk.

Treatment & Management

Urgent Assessment

Management focuses on urgent assessment, addressing underlying cardiovascular risk factors, and providing vision rehabilitation where vision loss persists.
Urgent eye assessment

Rapid evaluation is important because RAO can cause permanent retinal damage.

Vascular risk management

Conditions such as high blood pressure, diabetes and high cholesterol may need to be assessed and managed.

Cardiovascular assessment

Further medical evaluation may be recommended to identify underlying vascular problems and reduce the risk of future events.

Vision rehabilitation

Rehabilitation can help people adapt to lasting changes in vision and maintain independence.

Visual aids and support

Magnification, accessibility tools and other aids may help with everyday activities affected by vision loss.

Living With Retinal Artery Occlusion

Supporting independence

Vision loss following RAO can affect independence, mobility, work and daily activities. Vision rehabilitation and appropriate visual aids can help people adapt to changes in sight and maintain independence.

Take the Next Step

Early recognition, prompt treatment, ongoing monitoring, and continued research are helping more people preserve their vision and maintain independence.

Through collaboration between patients, researchers, clinicians, and communities worldwide, Retina International continues to support progress towards a future where retinal conditions are better understood, better treated, and more effectively managed.

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