Keratopathy Symptoms

Keratopathy Symptoms

Diabetes-related corneal alterations are frequent but under-diagnosed complications of both type 1 (insulin-dependent) and type 2 (non-insulin-dependent) diabetes. Corneal alterations include:

  • Delayed wound healing of the surface cell layer (epithelial cell layer)
  • Edema (swelling) 
  • Recurrent erosions (wearing away) of the corneal layers
  • Neuropathy/loss of sensitivity of the corneal surface
  • Tear film changes


The disease affects corneal epithelium (surface layer cells) and corneal nerves. Clinically observed corneal diabetes-related alterations include increased corneal thickness, epithelial defects ( surface layer cells that do not function properly), epithelial fragility and recurrent erosions, ulcers, edema, superficial punctate keratitis (small areas of cell death on the surface of the cornea, this can cause the eyes to become red, watering, and sensitive to light), delayed and incomplete wound repair, endothelial changes, and neuropathy exemplified by reduced corneal sensitivity 26.


Access the full bibliography here:

Newsletter Signup

To keep up to date with our news and activities,
please leave your details below

GDPR Compliance Please indicate your consent for Retina International to contact you via the email address listed for the purposes of general alerts and newsletters.